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au.\*:("FAIRLIE, David P")

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Results 1 to 25 of 27

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A new paradigm for protein kinase inhibition : blocking phosphorylation without directly targeting ATP bindingBOGOYEVITCH, Marie A; FAIRLIE, David P.Drug discovery today. 2007, Vol 12, Num 15-16, pp 622-633, issn 1359-6446, 12 p.Article

Nonpeptide ligands that target peptide-activated GPCRs in inflammationBLAKENEY, Jade S; FAIRLIE, David P.Current medicinal chemistry. 2005, Vol 12, Num 25, pp 3027-3042, issn 0929-8673, 16 p.Article

Synthesis of the Thiazole―Thiazoline Fragment of Largazole AnaloguesDINESS, Frederik; NIELSEN, Daniel S; FAIRLIE, David P et al.Journal of organic chemistry. 2011, Vol 76, Num 23, pp 9845-9851, issn 0022-3263, 7 p.Article

Macrocycles mimic the extended peptide conformation recognized by aspartic, serine, cysteine and metallo proteasesTYNDALL, Joel D. A; FAIRLIE, David P.Current medicinal chemistry. 2001, Vol 8, Num 8, pp 893-907, issn 0929-8673Article

MR1 presents microbial vitamin B metabolites to MAIT cellsKJER-NIELSEN, Lars; PATEL, Onisha; WILLIAMSON, Nicholas A et al.Nature (London). 2012, Vol 491, Num 7426, pp 717-723, issn 0028-0836, 7 p.Article

Modular α-helical mimetics with antiviral activity against respiratory syncitial virusSHEPHERD, Nicholas E; HOANG, Huy N; DESAI, Vishal S et al.Journal of the American Chemical Society. 2006, Vol 128, Num 40, pp 13284-13289, issn 0002-7863, 6 p.Article

A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitisWOODRUFF, Trent M; ARUMUGAM, Thiruma V; SHIELS, Ian A et al.International immunopharmacology. 2005, Vol 5, Num 5, pp 883-892, issn 1567-5769, 10 p.Article

Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injuryPROCTOR, Lavinia M; ARUMUGAM, Thiruma V; SHIELS, Ian et al.British journal of pharmacology. 2004, Vol 142, Num 4, pp 756-764, issn 0007-1188, 9 p.Article

A convergent solution-phase synthesis of the macrocycle Ac-Phe-[Orn-Pro-D-Cha-Trp-Arg], a potent new antiinflammatory drugREID, Robert C; ABBENANTE, Giovanni; TAYLOR, Stephen M et al.Journal of organic chemistry. 2003, Vol 68, Num 11, pp 4464-4471, issn 0022-3263, 8 p.Article

Towards Histone Deacetylase Inhibitors as New Antimalarial DrugsANDREWS, Katherine T; TRAN, Thanh N; FAIRLIE, David P et al.Current pharmaceutical design (Print). 2012, Vol 18, Num 24, pp 3467-3479, issn 1381-6128, 13 p.Article

Organic azide inhibitors of cysteine proteasesGIANG THANH LE; ABBENANTE, Giovanni; MADALA, Praveen K et al.Journal of the American Chemical Society. 2006, Vol 128, Num 38, pp 12396-12397, issn 0002-7863, 2 p.Article

Structural mimicry of two cytochrome b562 interhelical loops using macrocycles constrained by oxazoles and thiazolesSINGH, Yogendra; STOERMER, Martin J; LUCKE, Andrew J et al.Journal of the American Chemical Society. 2005, Vol 127, Num 18, pp 6563-6572, issn 0002-7863, 10 p.Article

Folding pentapeptides into left and right handed alpha helicesHOANG, Huy N; ABBENANTE, Giovanni; HILL, Timothy A et al.Tetrahedron (Oxford. Print). 2012, Vol 68, Num 23, issn 0040-4020, 4335, 4513-4516 [5 p.]Article

Ex Vivo Activity of Histone Deacetylase Inhibitors against Multidrug-Resistant Clinical Isolates of Plasmodium falciparum and P. vivaxMARFURT, Jutta; CHALFEIN, Ferryanto; PRICE, Ric N et al.Antimicrobial agents and chemotherapy. 2011, Vol 55, Num 3, pp 961-966, issn 0066-4804, 6 p.Article

Inhibitors selective for HDAC6 in enzymes and cellsGUPTA, Praveer K; REID, Robert C; LIGONG LIU et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 23, pp 7067-7070, issn 0960-894X, 4 p.Article

Antiproliferative and phenotype-transforming antitumor agents derived from cysteineGLENN, Matthew P; KAHNBERG, Pia; BOYLE, Glen M et al.Journal of medicinal chemistry (Print). 2004, Vol 47, Num 12, pp 2984-2994, issn 0022-2623, 11 p.Article

Protective effect of a new C5a receptor antagonist against ischemia-reperfusion injury in the rat small intestineARUMUGAM, Thiruma V; SHIELS, Ian A; WOODRUFF, Trent M et al.The Journal of surgical research. 2002, Vol 103, Num 2, pp 260-267, issn 0022-4804Article

Lysine Acetylation in Sexual Stage Malaria Parasites Is a Target for Antimalarial Small MoleculesTRENHOLME, Katharine; MAREK, Linda; GOODMAN, Christopher D et al.Antimicrobial agents and chemotherapy. 2014, Vol 58, Num 7, pp 3666-3678, issn 0066-4804, 13 p.Article

Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malariaANDREWS, Katherine T; FAIRLIE, David P; STOERMER, Martin J et al.Antimicrobial agents and chemotherapy. 2006, Vol 50, Num 2, pp 639-648, issn 0066-4804, 10 p.Article

Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in ratsARUMUGAM, Thiruma V; WOODRUFF, Trent M; STOCKS, Shelli Z et al.Journal of hepatology. 2004, Vol 40, Num 6, pp 934-941, issn 0168-8278, 8 p.Article

Antiarthritic activity of an orally active C5a receptor antagonist against antigen-induced monarticular arthritis in the ratWOODRUFF, Trent M; STRACHAN, Anna J; DRYBURGH, Nathan et al.Arthritis and rheumatism. 2002, Vol 46, Num 9, pp 2476-2485, issn 0004-3591Article

Inhibition of immune-complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonistSTRACHAN, Anna J; SHIELS, Ian A; REID, Robert C et al.British journal of pharmacology. 2001, Vol 134, Num 8, pp 1778-1786, issn 0007-1188Article

Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 proteaseTYNDALL, Joel D. A; REID, Robert C; HU, Shu-Hong et al.Journal of medicinal chemistry (Print). 2000, Vol 43, Num 19, pp 3495-3504, issn 0022-2623Article

Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic NicheSURYA KUMARI VADREVU; CHINTALA, Navin K; KARBOWNICZEK, Magdalena et al.Cancer research (Chicago, Ill.). 2014, Vol 74, Num 13, pp 3454-3465, issn 0008-5472, 12 p.Article

A refined agonist pharmacophore for protease activated receptor 2BARRY, Grant D; SUEN, Jacky Y; LOW, Heng Boon et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 20, pp 5552-5557, issn 0960-894X, 6 p.Article

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